Charak Clinical Research Center has just completed an NIMH (National Institute of Mental Health) funded study that has led to groundbreaking research, soon to appear in an internationally recognized publication.



Dr. Rakesh Ranjan is our lead site investigator at the Charak Clinical Research Center, an award-winning psychiatrist who has been practicing in the Cleveland area since 1993.
Charak Clinical Research Center has just completed an NIMH (National Institute of Mental Health) funded study that has led to groundbreaking research, soon to appear in an internationally recognized publication.
Additionally, we will soon be starting another NIMH funded study at Charak.
To increase our knowledge of the latest available treatments in behavioral health care, and to achieve the fullest understanding of our patients. This two-fold approach assures our patients of the best possible care.
Charak Clinical Research Center takes its name from the noted Indian physician from the 1st century, Charak, the author of one of the oldest books on medicine, The Charak Samhita. Charak was one of the first medical practitioners to champion the principles that knowledge of all available remedies, and a thorough understanding of the patient, are the critical elements to providing the most appropriate care for each unique individual
You can be on the forefront of innovation in the mental health space. Medications and treatments that were not previously available to you can be used to help you when you need it most.
The development of new medications plays a central role in the advancement of medical treatments and the improvement of patient quality of life. All new medications go through several stages or phases of testing to demonstrate their safety and effectiveness before physicians can prescribe them to their patients.
At the heart of this process are research studies called clinical trials. In a clinical trial, the new medication is typically compared to either a currently approved medication and/or a placebo (a pill that looks like the new medication but contains no active ingredients).
Each study is unique to itself, but each can offer many benefits to those who participate. Studies like these improve the overall treatment options for those with mental health conditions. If I want to participate in a study, all I need to do is call Charak to learn more information about it and to see if I may qualify.
A long term study of the safety & efficacy of VNS (Vagus Nerve Stimulation) as an adjunctive therapy to individuals diagnosed with Treatment Resistant Bipolar Depression compared to a no-stimulation control group.
18+ • Depression • Eligibility Form
This is a two-month long study evaluating the efficacy and safety of Caplyta (lumateperone) as a monotherapy for the treatment of major depressive episodes in bipolar and schizophrenic pediatric patients.
13-17 • Schizophrenia / BPD • Eligibility Form
An open label, yearlong study in the safety and tolerability of flexible dosing of FANAPT (iloperidone) in adolescent patients.
13-17 • Bipolar Disorder • Eligibility Form
A two-month-long study evaluating the safety and efficacy of Caplyta (lumateperone) in treating irritability in pediatric patients with autism as a monotherapy.
13-17 • Autism • Eligibility Form
This a device (non-drug) study that uses rTMS (repetitive transcranial magnetic stimulation) along with HIFEM (high-intensity focused electromagnetic stimulation) for combined treatment of depressive symptoms and urinary incontinence 2-60 months after childbirth.
22-60 • Depression • Eligibility Form
12395 McCracken Road, Suite E,
Garfield Heights, OH 44125
(216) 559 - 1360
research@charakcenter.com
Mondays: 9AM - 5:30PM
Tuesdays: 9AM - 5:30PM
Wednesdays: 9AM - 5:30PM
Thursdays: 9AM - 5:30PM
Fridays: 9AM - 5:30PM
Weekends: CLOSED
12395 McCracken Road, Suite E,
Garfield Heights, OH 44125
(216) 559 - 1360
research@charakcenter.com
Mondays: 9AM - 5:30PM
Tuesdays: 9AM - 5:30PM
Wednesdays: 9AM - 5:30PM
Thursdays: 9AM - 5:30PM
Fridays: 9AM - 5:30PM
Weekends: CLOSED
Yes! Although remarkable progress has been made over the past 20 years in defining and treating the various forms of mental illness, most treatments are either not effective for everyone or may produce significant side-effects in some individuals. As a result, there is an ongoing need for the development of new medications within the mental health field.
There is no single reason that individuals choose to participate in clinical trials but many do so in the hope that the new medication will provide them with relief from their symptoms, and produce few and/or mild side effects. Some choose to participate because they recognize that even if they do not experience a direct personal benefit from participating in the trial, the research study results will potentially increase the level of understanding of the disorder, and contribute to the development of more effective forms of treatment.
Participation in a clinical trial is completely voluntary. The decision to participate should only be made after thorough consideration of all available information. Before you enter a clinical trial, the study doctor and study staff will fully describe the purpose of the study, what is expected of each participant, and the potential risks and benefits that you may experience. All potential participants are presented with a document that contains this information as well as a complete description of each element of the trial. You must read, discuss and finally sign this document, called the “Consent Form,” before any study related procedures can be performed. Throughout the course of the trial, any new information that becomes available regarding trial procedures or medication will be provided to you in a timely manner. You can choose to end your involvement in a clinical trial at any time and for any reason.
Some of the benefits of participating in a clinical trial include: Taking an active role in your own treatment. The opportunity to receive treatments not otherwise available. Receiving skilled medical care at no financial cost. In many cases, participants are also compensated for their time. The opportunity to contribute to the current state of medical knowledge.